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ea0026p580 | Cardiovascular endocrinology and lipid metabolism | ECE2011

Relationship between plasma aldosterone concentration and soluble cellular adhesion molecules in patients referred to coronary angiography

Tomaschitz A , Pilz S , Ritz E , Grammer T , Amrein K , Boehm B O , Marz W

Introduction: An increasing notion suggests that aldosterone contributes to the development and progression of atherosclerosis and cardiovascular disease. Experimental studies documented an upregulation of cellular adhesion molecules, which are involved in the pathogenesis of atherosclerosis, after administration of aldosterone. However, evidence for an association between circulating aldosterone levels and soluble cellular adhesion molecules in humans is sparse.<p class="...

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ea0029p1378 | Pituitary Clinical | ICEECE2012

Low IGF1 levels are associated with a lower prevalence and incidence of anxiety disorders in primary care patients (DETECT cohort) and the general population (SHIP cohort)

Sievers C. , Auer M. , Klotsche J. , Pieper L. , Athanasoulia A. , Schneider H. , Marz W. , Nauck M. , Volzke H. , John U. , Freyberger H. , Friedrich N. , Biffar R. , Wittchen H. , Stalla G. , Wallaschofski H. , Grabe H.

Objective: In vitro and in vivo models revealed that the somatotropic system exerts central effects on the central nervous system. The objective of this study was to investigate for the first time whether varying endogenous IGF1 levels are associated with mental health outcomes, namely affective disorders, in humans.Design and methods: We included 6773 subjects from the DETECT study, a representative study on primary care patients in German...

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Endocrine Abstracts

Relationship between plasma aldosterone concentration and soluble cellular adhesion molecules in patients referred to coronary angiography

Low IGF1 levels are associated with a lower prevalence and incidence of anxiety disorders in primary care patients (DETECT cohort) and the general population (SHIP cohort)

BiosciAbstracts